Posted by Bob on January 15, 2007, at 1:20:30
In reply to Cymbalta an almost a year, posted by shadowplayers721 on January 15, 2007, at 0:40:03
> I didn't notice it right away, but Cymbalta has caused more weight gain than any antidepressant I have ever tried. People say, - 3 months and no weight gain. Give it 11 months and then see. Those trials aren't long enough in my opinion. I can go without eating a thing and the scale doesn't move. I can just drink fluids and the scale doesn't move. Something is wrong. I got my blood work checked and nothing shows. The weight just keeps climbing. I have NEVER been this heavy and this physical in my life. Something is up with this drug. I am wondering if it's in the same class as Remeron on the weight issue or worse. You don't have to eat to continue to gain. I am telling you - something is up with this drug. The FDA just issued a warning about it can affect the liver. It does work wonders for pain relief and depression.
I have long felt just what you have described. I gained significant weight on Anafaranil, Effexor, and pretty much all other SSRIs. It doesn't happen right away, but slowly, and insidiously. Just as you have said, no diet changes or amount of exercise seem to stave it off. IMO, weight gain is inevitable for most people on most SSRI/SNRI drugs. There is a misperception about this because the trials are indeed way to short. In fact, many adverse effects from these drugs become much worse and intolerable after long durations - many months or years. There is little data being collected for long term use. The drug companies have no motivation to find out, and many people can't stand to be on the meds that long anyway. Sure, people talk about how this or that med doesn't cause weight gain, or doesn't have as much sexual side effects, and so on, but in the end, if you're on it long enough, there are almost always negative results in these areas. Eventual general apathy and anhedonia is another one.
poster:Bob
thread:722417
URL: http://www.dr-bob.org/babble/20070113/msgs/722425.html