Re: ENSAM Question

Posted by SLS on January 14, 2007, at 11:48:44

In reply to Re: ENSAM Question, posted by halcyondaze on January 14, 2007, at 10:39:16

> It is my understanding that it is dose-dependent. The higher the dose, the higher the MAO-A inhibition, which is why they saw a steady increase in the tyramine pressor response as dependent upon dosage.
"selegiline administered by transdermal patch exhibited antidepressant properties only at doses that inhibited both MAO-A and MAO-B activity in the brain."
Perhaps the pressor response is dependent upon inhibition of gut MAO and not brain MAO?

- Scott

Thread

ENSAM Question blueberry1 1/13/07
Re: ENSAM Question SLS 1/13/07
Re: ENSAM Question SLS 1/13/07
Re: ENSAM Question halcyondaze 1/14/07
Re: ENSAM Question SLS 1/14/07
MAO-a inhibiton from EMSAM, tyramine metabolism psychobot5000 1/14/07

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