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can Remeron + Luvox be combined safely?

Posted by agjchs on January 12, 2007, at 17:06:32

Greetings,

I'm new to this board and am at the end of my rope with OCD (I'm 41 years old and have had it since before I was age 2). Have tried Paxil, Prozac, Anafranil (made me more depressed). Have been on Remeron 30mg for a year, and it's the best antidepressant I've ever taken (have taken them for 16 years), but it increased the OCD.

My psychiatrist wants to switch me from Remeron to Luvox (200mg to start, and work up to 400mg). The first night I went without Remeron, I started feeling weird physically and after doing some research on the internet, found out that others had withdrawal symptoms from Remeron and that one should taper off 7.5mg at a time (*none* of which my psychiatrist told me about).

But I have read that taking Remeron and Luvox together can cause serotonin syndrome and can increase Remeron levels by as much as fourfold ("An Overview of Psychotropic Drug-Drug Interactions" by Neil B. Sandson, M.D., Scott C. Armstrong, M.D., and Kelly L. Cozza, M.D.).

I have been tapering off Remeron (was at 22.5mg for two weeks, and am now at 15mg), and was wondering if I could *safely* take a small dose of Remeron (15mg) while "breaking in" Luvox with a small dose (50mg).

Also, I googled this site for Remeron and Luvox, and am pretty spooked by some of the Luvox horror stories I've read.

Thanks in advance for your replies.


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poster:agjchs thread:721753
URL: http://www.dr-bob.org/babble/20070107/msgs/721753.html