Posted by SLS on January 9, 2007, at 15:32:06
In reply to Re: pergolide, cabergoline: heart pathology via 5-HT2b » SLS, posted by ed_uk on January 9, 2007, at 15:23:38
> On the bright side, at least it doesn't apply to Requip and Mirapex.
On the other bright side, it may be that direct receptor agonism is necessary for the valvulopathy, and not an effect secondary to reuptake inhibition or release. I was impressed by the fact that fenfluramine had a metabolite that was a direct agonist.
- Scott
poster:SLS
thread:720797
URL: http://www.dr-bob.org/babble/20070107/msgs/720829.html