Posted by river1924 on January 8, 2007, at 0:30:39
In reply to Re: Tolcapone Improves Cognition Episodic Memory » river1924, posted by ed_uk on January 7, 2007, at 8:18:11
I did a bit more research after I posted this and realized the rules for a prescription are pretty strong and the rules for blood tests etc are difficult.
My pdoc is willing to prescribe a similiar drug called entacapone (Comtan) but there is no research on that and cognition because so little of that drug enter the CNS. (Tolcapone enter the CNS easily.)
I don't really understand what COMT (catchol-O-methyltransferase) inhibitors really do. For Parkinson's, the drug works in nerves outside the brain barrier. It prevents the body from breaking down dopamine. But it seems more complex than that and I don't get it.
Thanks Ed.
River.
poster:river1924
thread:719489
URL: http://www.dr-bob.org/babble/20070107/msgs/720340.html