Posted by Quintal on December 15, 2006, at 20:01:37
In reply to MAOIs Reversable vs. Non, posted by becksA on December 15, 2006, at 17:52:29
I have similar problems to you becksA and have tried Manerix, Parnate and Marplan (among a *huge* variety of other ADs and benzos). Similar story with the Klonopin. The highest dose I took was 20mg (illicitly) but my usual dose was about 4mg.
Manerix is generally considered ineffective for SA. One South African study concluded it had about 80% efficiency and another failed to show any response at all. Manerix did not work for me and I took it for six months at 900mg. I was also taking Klonopin at the time and Manerix still caused insomnia. I wouldn't recommend it during benzo withdrawal for that reason.
I would recommend Nardil over Parnate, as Nardil has a metabolite called phenylethylidenehydrazine (!) which studies suggest boosts GABA levels in the brain, thereby supposedly exerting the main mechanism behind Nardil's anxiolytic effect. I guess this would come in useful during benzo withdrawal?
Parnate is good as an antidepressant and antipanic, but tends to be stimulating and may make anxiety worse if taken without a benzo. Marplan is generally considered to be a weaker version of Nardil.
http://www.socialfear.com/nardil_increases_brain_gaba.html
Good luck.
Q
poster:Quintal
thread:714023
URL: http://www.dr-bob.org/babble/20061212/msgs/714073.html