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Re: So Effexor is just an SSRI if under 150-225mgs,huh

Posted by linkadge on December 12, 2006, at 16:19:14

In reply to So Effexor is just an SSRI if under 150-225mgs,huh, posted by qbsbrown on December 12, 2006, at 13:23:02

For clarification, effexor will affect norepinephrine at ANY dose.

The molecule affects serotonin and norepinephrine uptake in a certain ratio, and that ratio is fixed nomatter what dose.

When doctors say that higher doses are needed for norepinephrine effects, generally, they are referring to the fact that norepinephrine effects are not prounounced for (some) peopled untill higher doses.

As a counterexample however, I was taken off 75mg of effexor when it gave me high blood pressure. This is a noradrenergically mediated side effect that I don't get on SSRI's. So, it depends on the individual too. How sensitive they are to the noradrenergic effects.

Linkadge


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URL: http://www.dr-bob.org/babble/20061212/msgs/712934.html