Posted by blueberry on December 8, 2006, at 4:27:19
In reply to Re: Anyone tried Geodon for SA?, posted by SLS on December 7, 2006, at 10:58:53
> > Even in those cases, I think depakote and other mood stabilizers should be tried first for longterm use
>
> For schizophrenia?***Yeah, according to an excellent psychopharmacology website from a popular psychiatrist. It was in a recent thread.
> > Longterm antipyschotic use often results in problems worse than the original.
> How so?***Sleep disorders, metabolic disorders of all kinds, tardive dyskenisia, EPS, and psychiatric conditions that never existed in the first place.
> > Depending on how many years someone is on an antipsychotic, the odds of developing other neurological problems approahes 100%.***Another psychopharmacology website stated that the risk of EPS or tardive dyskenisia with any of the atypicals is about 15%-30% the first, and increases by 10%-15% each year, so that by year 8 you are approaching 100%. From my 10 year experience with a modest dose of 5mg zyprexa, I have developed all kinds of neuromuscular movement problems, sleep disorder problems, poopout problems, metabolic problems, and anxiety that never existed up until year 8.
> That's a pretty strong statement to make. Personally, I have not seen evidence in medical literature which describes such.***It's there. I mainly speak of my personal experience and observing other people's comments here over the years. It is a strong statement because I wish for fellow pbabblers to not experience the same crap.
> That being said, I wouldn't find the use of Geodon to be the usual treatment for SA. I certainly wouldn't want it to be used on me as the first-line treatment.
>
> - Scott***Everything is arguable in psychiatry. Literature from one source might differ from literature from another. Mileage varies. But when it comes to blocking dopamine receptors and messing with metabolic function the way atypicals do for many years, I think trouble is inevitable.
***My problems have improved about 30% since stopping 10 years of prozac. So the ssris are not without longterm risk either.
***I do know one lady who had psychotic schcizoaffective mania. She was started on zyprexa for the acute phase then tapered over to depakote and lithium. She remains symptom free on just medium dose lithium. Anecdotal report only.
***I think psychiatry is too complicated, genetics are too complicated, for any research or any literature to apply to every person. Literature is good for general guidelines I believe, but is by no means a bible.
***Personally I do believe atypicals are handed out like candy way too often for conditions they are not FDA approved for, and that since they are fairly new, it won't be until 20 or 30 years that the full risk of their use is well known.
poster:blueberry
thread:711083
URL: http://www.dr-bob.org/babble/20061206/msgs/711396.html