Posted by ed_uk on November 1, 2006, at 14:10:51
In reply to Re: Taking 12mg of Xanax cr per day and still panic! » ed_uk, posted by lukeds on October 30, 2006, at 22:00:35
Luke,
I don't think you need to worry about your liver. I am a lot more concerned about the potential for withdrawal symptoms when you reduce your Xanax.
Clomipramine's major metabolite potently inhibits the reuptake of norepinephrine. Clomipramine is also an antihistamine. Combining clomipramine with maprotiline would seem potentially dangerous, and the logic for such a combination is dubious. I am concerned that the risk of having a seizure may be especially high when clomipramine is combined with maprotiline, particularly if your Xanax dose was being reduced.
Given that you suffer from anxiety, clomipramine is a more logical treatment than maprotiline. This is why I suggested that you stop the maprotiline. The clomipramine + maprotiline + trazodone combination concerns me. It is a very unusual combination of antidepressants.
Regards
Ed
poster:ed_uk
thread:697995
URL: http://www.dr-bob.org/babble/20061028/msgs/699608.html