Posted by med_empowered on October 29, 2006, at 11:20:24
In reply to Re: Long term Olanzapine for BP....any comments? » ronaldo, posted by Phillipa on October 29, 2006, at 11:00:39
zyprexa has lower EPS and TD rates than, say, Haldol, but both can still occur, so do watch for that.
Adding metformin to the zyprexa may help reduce/minimize/reverse metabolic issues that pop up.
Abilify is different from zyprexa (generally not sedating, best taken in the morning, etc.) but it seems to have a low EPS rate and I don't think any cases of TD have been reported yet (although it is entirely possible this drug *will* cause TD, since it can suppress pre-existing cases of TD). Some people hate the first couple weeks; a beta blocker and/or benzo might be a good call for the initial period. Since ABilify can pump up or reduce dopamine levels (after inducing a state of low dopamine), it may be more tolerable than other APs out there.
Olanzapine boosts dopamine when mixed with Prozac (and probably other antidepressants as well)..alone it drops levels of most neurotransmitters. I imagine other APs have similar effects, but...who knows.
poster:med_empowered
thread:698653
URL: http://www.dr-bob.org/babble/20061028/msgs/698709.html