Posted by yxibow on October 27, 2006, at 3:20:45
In reply to Re: Phenobarbital for Anxiety » yxibow, posted by ed_uk on October 26, 2006, at 13:50:19
> Hi J
>
> >High or low potency (number of tablets and milligrams), its the dosage that works that counts, Klonopin or Valium really share similarities in long half lives (although Klonopin is usually dosed twice daily because the actually half life may be less than a day), although I swear now more by Valium for anxiety.
>
> There is a tendency to prescribe diazepam at subtherapeutic doses. Clonazepam is more likely to be prescribed at doses that actually help. In this way, the high potency of clonazepam is relevent.
Only because of the "mother's little helper" doctor syndrome. Its actually as safe as it gives a 24 hour window or more. Klonopin is milligram for milligram not particularly different in the grand scheme of things except that in some people it can have a half life of as little as 16 hours, thus twice daily dosing.
> >There's also the slightly more esoteric Serax (oxazepam) which is another anxiolytic benzodiazepine (lower potency, higher dosing may be necessary but generally doesnt go through the liver.)
>
> You certainly like the work 'esoteric' J! I think oxazepam is probably best reserved for elderly or debilitated patients who may have trouble metabolising other benzodiazepines....."trouble metabolizing..." It was just a suggestion for a fellow who may not have tried it, even if it is as ineffective for anxiety as Librium except at high doses.
-- Jay
poster:yxibow
thread:697393
URL: http://www.dr-bob.org/babble/20061020/msgs/698106.html