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Re: treatment resistance what has worked for you?

Posted by Another Phil on October 2, 2006, at 23:08:15

In reply to Re: treatment resistance what has worked for you? » Another Phil, posted by Jost on October 2, 2006, at 11:02:10

> Could it be that the combination of Emsam and Parnate pushed you over the edge, given that the Emsam wasn't at all out of your system?

I suspect that that contributed to it. Also, I had just tapered off of a relatively low dose of Effexor about a week earlier. Even though Effexor has a very short half life, I don't know how long after discontinuing it its effect on neurotransmitters persists. (See my complaints about my pdoc, below).

> If so, maybe things will even out over time.

Actually, things have evened out quite nicely for me (with the obvious exception of the side effects I mentioned). I'm back to working out and running every other day, which was unimaginable while I was sick from the Depakote side effects.

> Your Pdoc must be very comfortable with Maois to go for that course-- many approach them with diffidence, if not dislike.

Apparently, he has a fantastic reputation; since everyone I've spoken to in his field seems to have heard of him and thinks highly of him. However, he has done several things over the past few months to make believe that he's a bit reckless, cavalier about MY side effects, and, maybe not as knowledgeable as his reputation suggests. I can post details if anyone is interested; it's probably not relevant though. I have gotten recommendations for another Pdoc from several sources and will try to get an appointment with him soon, if for no other reason than a second opinion.

> At what point, would you say, you got to the mix of meds you're using now? about the middle-end of August? cause that really isn't that long, when you're talking about changing so many intense drugs, with such rapidity.

That's about right. The daily cycling stopped when I started taking Depakote, but since I had been so miserable before, I didn't realize that the Depakote was causing all sorts of other side effects, basically making me feel weak and ill all the time. Once I replace it with Lamictal (probably late August), I felt immediately better.

> Btw, do you do all the usual things re: constipation, that you might not have to do, but that are simple, like drinking enough water (v.important) and eating bran (or something with lots of insoluble fiber). I've had experience with someone who had a severe problem in that respect, and it can be hard to treat. But let me know if you need any (not medical, but at least experienced) advice.

Yes. I've done it all. Nothing seems to work but laxatives: a combination of peri-colace and magnesium-based laxatives.

Thanks for the concern and advice. Let me know if I can tell you anything else that might help you.


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poster:Another Phil thread:690651
URL: http://www.dr-bob.org/babble/20060927/msgs/691368.html