Posted by Squiggles on September 28, 2006, at 7:58:36
In reply to Re: Check this out bipolars!! » Squiggles, posted by SLS on September 27, 2006, at 23:50:57
BTW,
I just found this excerpt from a recent article
by Dr. Charles Bowden on Lithium (he recommends
Quetiapine or other drugs, all preferable to
lithium. I have never agreed
with Bowden on almost anything he says. He
has always bashed Lithium."Lithium may well have the least potential to improve function due to the large number of adverse effects, particularly cognitive, many of which worsen with age and duration of treatment. There is evidence that patients with
bipolar disorder have significant cognitive deficits, even when asymptomatic (Atre-Vaidya et al 1998; van Gorp et al 1998), which are closely related to psychosocial and functional impairments. Moreover, lithium may lead to
induction of depressive symptomatology which may further impair functionality (Bowden, Collins, et al 2005).
Conversely, mostly open studies compared with normative data suggest that lithium may reduce suicidal behavior even when not effective as a mood stabilizer (Tondo et al 2001)."from:
BIPOLAR DISORDERS: TREATMENT OPTIONS AND PATIENT SATISFACTION
Charles Bowden
Vivek Singh
Department of Psychiatry, The
University of Texas Health Science
Center at San Antonio, San Antonio,
TX, USAAbstract: Functional recovery, the goal of treatment, has long been overlooked in the
assessment of effectiveness of pharmacological treatments. However, with the recent shift in
paradigm, from syndromal symptomatic recovery to functional recovery, there appears to be
a new interest in the definition and evaluation of functional recovery. Since functional recovery
lags symptomatic recovery, sometimes by months or years, the attainment of functional
recovery will be determined by both efficacy and long-term compliance. Quetiapine, due to
its efficacy in both mania and depression, and effect on cognition may lead to improved
functioning in patients with bipolar disorder.
Keywords: bipolar disorders, syndromal recovery, functional recovery, efficacy, effectiveness/
in*Neuropsychiatric Disease and Treatment 2006:2(2) page 151.*
Squiggles
poster:Squiggles
thread:689613
URL: http://www.dr-bob.org/babble/20060927/msgs/689847.html