Posted by notfred on September 26, 2006, at 21:38:09
In reply to genetics of schizophrenia, posted by alexandra_k on September 26, 2006, at 20:45:15
>'This core 7-marker haplotype was present in 7.6% of 394 controls and 14.4% of 402 independent affecteds, thereby conferring a relative risk of around 2.1 (p=0.000087)'
I'm not sure how they get from 7.6% of people without schizophrenia having the 7-marker haplotype and 14.4% of people with schizophrenia having the 7-marker haplotype to this:
>'On the basis of these frequencies and relative risks, the 7-marker haplotype has a population attributable risk of 16% under a multiplicative model, indicating that 16% of schizophrenia in Iceland could be eradicated if the haplotype were - in theory - eliminated from the Icelandic population (Stefansson et al., 2002)'
Maths aside this part is very troubling:if the haplotype were - in theory - eliminated from the Icelandic population
poster:notfred
thread:689461
URL: http://www.dr-bob.org/babble/20060919/msgs/689471.html