Posted by linkadge on September 23, 2006, at 17:12:16
In reply to Re: Nicotine works :s, posted by SLS on September 23, 2006, at 9:51:42
I'll keep looking for the exact study I am looking for.
Apparently nicotine acts as an agonist of 5-ht1a autorecpeotrs, especially sensitive to those in the dorsal raphia neucleus. Long term administration may downregulate autoreceptor function.
I got this hit when searching, but I can't acess find the abstract, this may have been the one I was looking for:
Depression and Nicotine: Preclinical and Clinical Evidence for ...Another action of nicotine, which may be analogous to that of some serotonergic antidepressants, is that nicotine downregulates the expression of 5HT1A ...
www.current-reports.com/article.cfm?PubID=PR03-6-1-05&Type=Article&KeyWords= -
poster:linkadge
thread:687688
URL: http://www.dr-bob.org/babble/20060919/msgs/688490.html