Posted by SLS on September 23, 2006, at 6:18:08
In reply to Re: Nortriptyline » zeugma, posted by tensor on September 23, 2006, at 4:27:31
> > buspar works best when taken over a long period of time.
>
> Yes i know, but it is something i have found out myself. It seems to boost noradrenaline, if i feel somewhat depressed and i take 10-20mg of buspar at bedtime i often wake up very energized. Exactly the same feeling as when you are taking a too high dose of e.g. remeron, edronax or nortrip. This probably works on a very few people. Sometimes i take buspar prior to sex to counteract the sexual s/e of nortrip, this also often works fine. I do only take buspar p.r.n.
Buspar (buspirone) is metabolized extensively into 1-PP. 1-PP is a NE alpha-2 autoreceptor antagonist just like Remeron and yohimbine. This mechanism produces an increase in the synthesis and release of norepinephrine. I mention yohimbine because it is sometimes suggested as an aid to counteract sexual dysfunction and, before the availability of Remeron, was sometimes suggested in the treatment of treatment-resistent depression.
- Scott
poster:SLS
thread:688067
URL: http://www.dr-bob.org/babble/20060919/msgs/688386.html