Posted by linkadge on September 17, 2006, at 10:14:15
In reply to Re: Nicotine and Depression, posted by linkadge on September 17, 2006, at 9:48:32
I mean honestly, if you saw us group of depressed people sitting around on a porch step, popping our effexors, and our prozacs, you'd start to think that these agents were not antidepressants either :)
Here is a very instersting study that states that the Nicotine Actycholine receptors are respondiable for the antidepressant effects on the TCA drug amitryptaline. It states that mice lacking such receptors are resistant to its effects. The flinders sensitive line seem to show imballances in serotonin/acetycholine/dopamine. Nicotine administration itself produces a functional inhibition of these receptors.http://www.yaledailynews.com/Article.aspx?ArticleID=26692
Another study from:http://www.lorenbennett.org/nsmok.htm#patch
Transdermal nicotine patch lessens depression
The role of repeated nicotine administration on sleep and major depression was studied in tests. Twelve nonsmoking volunteers: six major depressed patients and six normal patients. All subjects underwent t: acclimatization, control night, four nicotine nights (transdermal patches) and one withdrawal night. Nicotine increased REM sleep time in both groups and an average reduction the seriousness of depression of 43.9% in the depressed patients. These findings suggest that nicotine receptor activation may be important in major depression, and shows that nicotine patches may be useful in the treatment of depression.
Some others:
http://www.jointogether.org/news/research/summaries/2006/nonsmokers-depression-lifted.html
http://www.sciencedaily.com/releases/2002/12/021211083430.htm
http://www.sciencenews.org/articles/20020511/note17ref.asp
Linkadge
poster:linkadge
thread:686441
URL: http://www.dr-bob.org/babble/20060909/msgs/686766.html