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Opinions on switching from Lex to Prozac

Posted by Roy Joseph on September 15, 2006, at 9:13:00

I have been treated for OCD/GAD and mild depression on/off for the past eight years. Recently, I went back on medication -this time to Lexapro - but was unable to get up to a dose necessary to really help with the OCD. (I have also done extensive therapy and have been strongly committed to CBT and doing the homework).

Currently, I am on 7.5mg of Lexapro, but cannot go any higher without irregular heartbeats, dizziness, and terrible migraines. Together, my doc and I thought that Prozac (a drug used in the past) would help. I am also taking Nefazodone 150mg a day. My concern is switching to Prozac because of the following:

1). If I simply substitute (with no weaning on/weaning off) the Prozac for the Lex, will I likely have a relapse of the OCD?

2). If a relapse is likely, is it better to slowly wean off Lexapro while slowly adding in Prozac?

3). Will the Serzone help mitigate any negative withdrawal effects of Lexapro?

Thanks much!


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poster:Roy Joseph thread:686162
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