Posted by jealibeanz on August 30, 2006, at 18:57:12
MAOI's were the first antidepressants available for use. The biggest drawback to their use was that they had many interactions with drugs and foods, because they were MAOI-A drugs. Once we had the availability of newer agents, like Prozac,we didn't use these agents any longer(except in rare instances) due to these disadvantages.
Selegilene is an MAOI-B agent, which has been used in Parkinson's disease. It is unlikely to cause weight gain, as previously stated, as it usually causes weight loss as a side effect.
It has a stimulating effect,as in it keeps people awake at night, etc. It is not a "stimulant" such as Strattera. However, it is possible that you could experience some benefit from this medication with your ADHD, since this medication acts on Norepinephrine, Dopamine and Serotonin. This medication has not been studied in the treatment of ADHD.
It is true that at the higher doses it is possible for Emsam to work at MAOI-A. It is more selective for MAOI-B, but this is lost at higher doses. When used at the 2 higher doses, one must use the dietary restrictions that the older antidepressants had. Even at the lower doses, there would be an
effect on serotonin.
poster:jealibeanz
thread:681574
URL: http://www.dr-bob.org/babble/20060825/msgs/681574.html