Posted by linkadge on August 30, 2006, at 17:33:41
In reply to Another interesting article, posted by Jimmyboy on August 30, 2006, at 14:19:25
Yeah, thats right, it is a pathway of dopamine and norepeinephrine metabolism.
The flavanoid quercetin is also a COMT inhibitor, but it is also a MAO-A inhibitor! Quercetin is active in animal models of depression.
I have combined COMT inhibitors with MAO-B inhibitors and they do have synergistic effects, though I'd just caution the use of MAO-B, COMT, and DAT inhibitors in combination.
Linkadge
poster:linkadge
thread:681230
URL: http://www.dr-bob.org/babble/20060825/msgs/681536.html