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Re: Sibutramine (Meridia) - Day 26 - Discontinued

Posted by SLS on August 30, 2006, at 17:15:23

In reply to Re: Sibutramine (Meridia) - Day 25 - Discontinued, posted by SLS on August 30, 2006, at 7:32:58

7 days @ 10mg
12 days @ 20mg
7 day @ 0mg


I can see that this is not going to be a rapid or smooth disappearance of whatever worsened state sibutramine left me in. Today was almost as bad as two days ago. The middle of the day was the worst. It may be that sibutramine produced a downregulation of NE alpha-2 receptors as was reported in one study. This might be detrimental to me as the NE alpha-2 antagonist, idazoxan, exacerbated my depression significantly.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=Display&DB=pubmed

Currently:

nortriptyline 100mg
Lamictal 150mg
Topamax 100mg
Abilify 10mg


- Scott

 

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