Posted by psychobot5000 on August 28, 2006, at 20:13:10
In reply to Re: Dopaminergic-based pharmacotherapies for Depre, posted by jealibeanz on August 28, 2006, at 16:44:15
________
In my opinion, people with ADHD, depression, anxiety, ect. do not seek drugs because of past antidepressant or stimulant use, it's because there's a true dysfuntion in their brains. We recognize this in ourselves and sometimes come upon substances with can relieve our symptoms partially.
_________I can only assume that addiction takes -both- the addictive substance, and a disposition on the part of the person, either in character or biology.
The case of amineptine is particularly frustrating because, to the extent that it was studied, it seemed such a clean drug. The modest scale of its abuse potential is evident in the case studies: most amineptine abusers are documented as having previous dependence on opiates, cocaine, alcohol, cannabis, etc. The same holds true for abusers of tranylcipromine, prozac, and tianeptine--they nearly all have histories. This suggests to me that it takes a particular kind of person to make amineptine abuse a problem. Not that patients who benefited from it are unbiased (nor should they be), but many of them seem baffled by the attention payed to it.
Since I am not aware of it being possible to synthesize amineptine on the street, the way meth labs make possible that epidemic, I can't say removing amineptine makes sense to me. What danger was there? The abuse potential was not so great, and if it had to be carefully synthesized, then the source could be controlled. Perhaps the issue of drug-induced liver disease was more serious than we tend to realize.
I can only guess why Minaprine isn't available as a substitute dopaminergic antidepressant. Some pieces in the archives here make it sound very attractive.
poster:psychobot5000
thread:680536
URL: http://www.dr-bob.org/babble/20060825/msgs/680977.html