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3 day results for low-dose amisulpride

Posted by psychobot5000 on August 25, 2006, at 18:23:57

3rd day on 50mg amisulpride, added to previous regimen of 37.5 mg tianeptine, daily, in hopes of getting better antidepressant effect.

So far, I believe I have had a modest boost in mood-level, but the experience is greatly complicate by side-effects. I have experienced:


A mild increase in insomnia

Fatigue and daytime somnolence, independent of not-sleeping. Similar to 'leaden fatigue' experienced by atypical depressives, in which body and limbs feel too heavy to move

Bradycardia--relative to my normal state, my heart beats slower. I just measured my pulse at 60 per minute--about 15 lower than I would normally expect it to be. I have not checked my blood-pressure.

Some anterograde amnesia(a form of memory loss, where new events are not transferred to long-term memory. The sufferer will not be able to remember anything that occurs after his attention is shifted away from one subject for more than a few seconds)
____________________

Whatever mood and motivation benefits I'm getting (and I probably am getting some), seem to be obscured by the fatigue and other side-effects. It is a strange experience, but hopefully some of the side-effects will disappear or reduce to a point of manageability.

Here's hoping I can drag something good out of this. I am considering switching to Mirapex for broadly similar D2/D3 effects--this is, after all, a rather difficult experience. Perhaps reducing the dose to 25mg or so would reduce side-effects?

Pbot


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poster:psychobot5000 thread:680093
URL: http://www.dr-bob.org/babble/20060825/msgs/680093.html