Posted by finelinebob on August 21, 2006, at 0:09:34
In reply to Males with atypical depression- TCA or MAOI??, posted by Jimmyboy on August 20, 2006, at 8:30:23
> Also saw some stuff that said women with atypical depression respond better to MAOI;s and men with it respond better to tricyclics. Does anyone have any information on this?
Only from personal experience. And half the story. Never had to try MAOIs. Nortriptyline turned the tide for me. My PDoc picked it because of all the "dirty" TCAs -- and they're all dirty little drugs, aren't they -- nortrip was seen as the least dirty ... that and imipramine.
Personally, I found SSRIs toxic ... pretty dang dirty to me. On the other hand, I had a few of the typical nortrip side effects for about 2 weeks then other than keeping my weight up (SSRI buffet had already given me an extra 30-40lbs) I've been free of side effects.
The way I see it, the neurochemical reaction that might be a "main effect" for one person can be someone else's "side effect" if you didn't need it. I have no problems with serotonin. I have problems with norepinephrine. I have side effects with SSRIs. I have clean results with TCAs.
Given the dietary restrictions and other concerns with MAOIs, take the easier road first. My $0.02.
poster:finelinebob
thread:678298
URL: http://www.dr-bob.org/babble/20060818/msgs/678638.html