Posted by SLS on August 14, 2006, at 8:00:50
In reply to Re: Is Kramer right?, posted by SLS on August 12, 2006, at 21:46:43
> > What he's actually saying, to paraphrase as best as I can understand, is that people prone to multiple bouts of depression are people who have a defect in brain repair.
>
> As opposed to a defect in brain regulation?
>
> I think the latter is closer to the truth.
Depression appears to be a complicated illness with a multiplicity of factors contributing to its induction and persistence. Right now, I still don't think that it is a defect in brain repair that is responsible for its induction. I believe this to be more a product of dysregulation in neurotransmission and circuitry. However, I can see how such a defect could contribute to its persistence. I guess the illness might progress as a self-reenforcing process, with the inability of the brain to recover from stress-induced cell loss hindering the reestablishment of healthy interactions between entire circuits. Still, this is probably a matter of a diminished rate of repair rather than its complete absence as has been demonstrated by the recovery of brain tissue seen with lithium and antidepressant use.
- Scott
poster:SLS
thread:675829
URL: http://www.dr-bob.org/babble/20060810/msgs/676279.html