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Re: emsam 6 mg/24 = ? oral selegiline?

Posted by helpme on July 10, 2006, at 1:28:03

In reply to Re: emsam 6 mg/24 = ? oral selegiline?, posted by SLS on July 9, 2006, at 11:19:46

Yes, I understood that the "6" patch has an equivalent of 20 mg oral in it, but it takes 24 hours to seep out. But what you say about the metabolization making it more available and potent than the oral really does make it very confusing.


> 6mg/24 Emsam = 6mg oral selegiline
>
> The thing is, most of the oral selegiline gets degraded before it ever gets into the main blood stream due to first-pass metabolism in the liver. Therefore, the resulting therapeutic blood level of an equivalent amount of Emsam is much, much higher. I don't happen to know the equivalency.
>
>
> - Scott


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