Posted by linkadge on July 8, 2006, at 0:17:52
In reply to Re: BuSpar - an underused med with great potential?, posted by jflange on July 7, 2006, at 22:44:51
I've never heard of buspar causing dependance, at least not at the same level as SSRI's and benzodiazapines.
I think that buspar could probably help a number of people as an augment to SSRI's or alone.
This is the one medication that I really have wanted to try for a while.
If it does poop out, you may be able to regain efficacy with the use of melatonin. Melatonin has the ability to sensitize the 5-ht1a receptors. Ginkgo too, has the ability to restore decline in the population of 5-ht1a.
Cortisol decreases the activity of an enzyme that codes for 5-ht1a. So its probably a catch 22. Stress causes 5-ht1a loss, and 5-ht1a loss causes anxiety, breaking the loop somewhere might help.
There are a *lot* of medicinal herbs out there which probably derive their activity from 5-ht1a agonism.You could perhaps combine it with periactin, a 5-ht2a/c antagonist for increased anti-anxiety effect.
Linkadge
poster:linkadge
thread:664294
URL: http://www.dr-bob.org/babble/20060701/msgs/665023.html