Posted by Pops_1 on June 26, 2006, at 12:53:24
In reply to Re: Emsam and Attention Problems?, posted by Another Phil on June 23, 2006, at 14:04:42
> Thanks, Pops_1. Actually, I never stopped taking Dexedrine. I'm still taking 15 mg spansules twice a day, which made a noticeable difference in my ability to concentrate before starting Selegiline/Emsam, but has no effect now. In fact, my ability to concentrate now (Selegiline, Dexedrine, and all) is much worse than my original baseline without stimulants. For what it's worth, I haven't had any negative physical side-effects while combining them either.
>
> Also, is there anyone out there who has had any experience with Selegiline/Emsam in combination with Effexor or Zyprexa? I know the Effexor-Selegiline combination is warned against in the official literature, but my psychopharmacologist said it was OK, and I had been taking Effexor and Zyprexa beforehand with useful, but limited antidepressant effect.
Two things:1 - Dexedrine/EMSAM/Attention - Did you consider >reducing< your dexedrine dose to see if that helped? One of EMSAM's metabolites is itself an amphetamine, and maybe the stimulation producing by EMSAM and/or this metabolite is revving you up so much that you're more distracted than you were without any drugs. I know when I really upped my Dexedrine doses I was overexcited and distractable, maybe your combo is producing net negative effects at previously effective doses.
2. Effexor - Combining MAOI's with other ADs that affect serotonin is contraindicated to guard against "serotonin syndrome". I know effexor targets Serotonin (and norepinephrine), which would seem like the basis for contraindication. while I've seen doctors try contraindicated combos (MAOIs & wellbutrin, MAOIs + TCAs), usually this is for treatment resistant conditions or to counteract side effects. Given that the MAOI+SSRI prohibition is one rather religiously adhered to, I would personally be wary of combining Effexor + EMSAM given the risks. On the other hand, a qualified psychophamarcologist should know what they're doing...
poster:Pops_1
thread:660319
URL: http://www.dr-bob.org/babble/20060623/msgs/661602.html