Posted by notfred on June 14, 2006, at 17:50:40
In reply to Re: EMSAM stronger than oral selegline, posted by Pops_1 on June 14, 2006, at 17:22:25
>
> b. MAO-A inhibition is what produces antidepressant efficacyI have already posted studies to bear out this.
>
> c. MAO-A inhibition is what creates dietary restrictions
>see http://www.biopsychiatry.com/pressor.htm
Monoamine oxidase inhibitors
and pressor response to dietary amines
by
Tipton KF
Department of Biochemistry,
Trinity College Dublin, Ireland.
ktipton@tcd.ie
Vopr Med Khim 1997 Nov-Dec;43(6):494-503"Because gastro-intestinal monoamine oxidase (MAO) effectively prevents dietary pressor amines, typically tyramine, from entering the tissues, a marked hypertensive response (the "cheese reaction") can occur when subjects treated with antidepressant MAO inhibitors ingest foods or beverages rich in such amines. Although tyramine is a substrate for both MAO-A and -B, it is only inhibitors of the former enzyme"
poster:notfred
thread:655515
URL: http://www.dr-bob.org/babble/20060610/msgs/657006.html