Posted by SLS on June 11, 2006, at 11:46:14
In reply to Re: Klonopins relationship to serotonin » SLS, posted by zeugma on June 11, 2006, at 10:22:53
Thanks for replying, Zeugma.
> The VTA has projections afferent to the entire PFC (the "mesocortical" pathway). It also projects to the striatum (the "Mesolimbic" pathway). There is also a "mesocoerulear" pathway to the locus coeruleus affecting the NE system.
>
> The VTA, like the LC, is in the brain stem.
>
> The accumbens is next door to the amygdala, and both are posterior to, and below, the cortex.
>
> I wish I knew why AD's poop out so rapidly for you. Why do you think the DLPFC is involved?
Because of how cognitively affected and mentally slowed I am. I have almost no short-term memory. It is as if my executive functions have been dampened or poorly stimulated. I also display a "deficit syndrome" that probably involves hypoactiviy in limbic areas. I was wondering if there were hypoactive limbic afferents to the DLPFC that might not be stimulating that area enough. Perhaps it is the other way around. Maybe a hypoactive DLPFC fails to stimulate reward centers. Maybe deficiencies in the LC fail to stimulate the DLPFC directly or indirectly.Which comes first, the chicken or the egg?
Contrary to how I might appear in my writing, I literally cannot read beyond 2 or 3 sentences. Long paragraphs are overwhelming, and I must resort to skimming.
- Scott
poster:SLS
thread:654917
URL: http://www.dr-bob.org/babble/20060610/msgs/655490.html