Posted by Racer on May 26, 2006, at 0:54:09
In reply to Re: What should I consider for long term treatment, posted by jealibeanz on May 26, 2006, at 0:36:21
> Just another wondering... if Straterra does not cause weight gain, does that mean that it's most likely linked to Serotonin reuptake in my case? I know it's impossible to actually say one way or the other. Would EMSAM have much Serotonin action. I understand that it's not the same as a reuptake inhibitor, however, is the end result somewhat similar?
1. Serotonin is most likely part of the mechanism for weight gain. Three of the major serotonin receptor types are directly involved in the whole hunger/motility/digestion thing. In general, about 95% of the serotonin in your body is in your gut. That means that anything that changes the serotonin system is likely to change eating behaviors.
2. MAOIs do affect serotonin, but in a very different way. Rather than interfering with the serotonin transportase, they interfere with monoamine oxydase, which is the mopping up crew for worn out monoaminic neurotransmitters. I don't know much about how it all works, but it does mean that there are similarities, but also great differences.
Nardil, though, is known for weight gain, but Parnate is said to be weight neutral.
Hope that helps, and is not too incoherent...
poster:Racer
thread:647484
URL: http://www.dr-bob.org/babble/20060525/msgs/648688.html