Posted by madkat02 on May 19, 2006, at 11:37:18
In reply to Re: YXibow, LarryHoover, Blueberry, Ed, Link, SLS? » UgottaHaveHope, posted by yxibow on May 19, 2006, at 1:43:43
> > I am absolutely ravaged every day by anxiety. Its like my body is still and my motor (energy) is going 100 miles per hour. It's a overwhelming sense of fear and I don't even know what I fear.
> >
> > I've tried Klonopin (still taking), Xanax, Buspar, and most of the SSRI's. The only thing that touched it at all in 10 years was Seroquel. Anyone know why? Anyone have any suggestions on what else to try? Thanks Michael
>
>
> Actually I would hesitate to theorize on all sorts of speculations including that you say you have an internal motor energy which may be dampened by the D2 effects of Seroquel although that is just amateur drawing at straws....
>
> Neuroleptics are fairly powerful anxiolytics for certain disorders which for unknown reasons are not solved by other medications. Another posture that is more likely is that the sheer sedation from Seroquel and the 5HT effects are dampening an overactive mind perhaps in the OC Spectrum.
>
> If that is the case you may be helped by a combination of an SSRI and Seroquel (e.g. Luvox+Seroquel, Celexa+Seroquel, etc.)
>
> And one could also venture into the concept that you have a slight bit of psychosis attached to perhaps something more in the manic/bipolar spectrum, but that is getting a bit pejorative and in the realm of "practicing medicine without a licencse." (Well of course all conjecture really is -- we can only give a possibility.)
>
>
> If we look back at all the medications, the only thing in common is that the SSRIs and the Seroquel both act on serotonin, but they do in a completely different way. SSRIs block the reuptake of serotonin into synapses (I'm simplifying things) while Seroquel forms a blockade of serotonin outright, at among others 5HT2. The only other component is the D2, which is only in the Seroquel, and the huge component of H1 (antihistamine and drowsy effect.) The BuSpar you took is actually a "failed antipsychotic" that is used for anxiolytic relief with about 1/3 of the population reporting some relief.
>
> I'm not sure on the doses of Klonopin or Xanax you took -- you might not have had a enough of a dose to counteract whatever is going on inside.
>
> That's the thing here, I think that while better living through chemistry is great -- you obviously identify an anxiolytic disorder, I conjectured a whole variety of possibilities but they're really just pulling rabbits out of a hat -- I think that some psychotherapy and possible psychological testing if your insurance or monetary situation allows you to do these things as they may shed more light on the center of your fear. This doesn't mean you shouldn't continue taking the medication that is helping you along with that process.Hi I have one thing to say, even though I don't completely understand all that has been stated above. I experienced EXTREME anxiety and fear when I was on Xanax. When I finally saw a Psychiatrist instead of a regular M.D., she told me that Xanax causes rebound anxiety in most people and she personally never prescribes it. In addition to this my psycologist insist that it is also very bad. She has known several people to die from Xanax and alcohol combonation. Maybe talk to your doctor about this being a possibility of not being able to calm down. It feels as if you are about to crawl out of your skin, I know hang in there.
poster:madkat02
thread:645701
URL: http://www.dr-bob.org/babble/20060515/msgs/645896.html