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Re: Which neurotransmitters does Parnate affect?

Posted by djmmm on May 16, 2006, at 21:41:38

In reply to Which neurotransmitters does Parnate affect?, posted by Don_Bristol on May 16, 2006, at 19:14:22

Parnate increases all monoamines-- the catecholamines (Dopamine, norepinephrine, and epinephrine), Serotonin, Histamine, and many other trace amines.

Some studies of long term exposure to MAOI's, show a greater increase in Serotonin, as opposed to the other monoamines-- regardless of the fact that Parnate is a non selective MAOI

Some studies also suggest that Parnate has the ability to block the re-uptake of catecholamines.

Nardil is unique in that one of it's metabolites is a inhibitor of GABA transaminase, as a result, GABA is increased.


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