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Re: Loratadine for SSRI's sexual dysfunction

Posted by SLS on May 15, 2006, at 13:12:43

In reply to Loratadine for SSRI's sexual dysfunction, posted by Maximus on May 15, 2006, at 12:34:46

> "http://miniurl.org/lvp"
>
> "An open-label series using loratadine for the treatment of sexual dysfunction associated with selective serotonin reuptake inhibitors."
>
> **************************************
>
> Hi,
>
> Yes that's the good old Claritin, an antihistaminic. I tried it and it works very well. 20 mgs were needed to relieve the sexual side effects from Effexor 150 mgs. Loratadine targets all departments except the libido.
>
> May be a partial solution in waiting for a clean 5HT2A antagonist?

They already exist. The trick is to convince a drug company that there will be a profit in marketing such a drug. Ritanserin is an example of a drug that is a selective antagonist for 5-HT2a/c receptors. It would probably make a good adjunct to SRI drugs to increase efficacy and reduce side effects. It is a good drug without a good reason to develop beyond its use in the laboratory.


- Scott

 

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poster:SLS thread:644267
URL: http://www.dr-bob.org/babble/20060515/msgs/644287.html