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Re: Statistical question on SSRIs - ADDENDUM » Larry Hoover

Posted by Squiggles on May 13, 2006, at 9:59:43

In reply to Re: Statistical question on SSRIs - ADDENDUM » Squiggles, posted by Larry Hoover on May 13, 2006, at 8:35:14

Please be patient - I am reading it now.
It's important because so many scientists
and lawyers and victims are giving testimony
before the FDA and at an early period of the
drug's development.

As far Dr. Nemeroff is concerned, his
contention that "testimonials" and "anecdotes"
are not scientifically significant, is not
a strange idea in statistical validity. But I
see some counterexamples by Fitz which i will
go into later.

As for depression and its suicidality, and
a causal relation, imho this does not exclude
the possibility of suicidality in drug withdrawal,
inappropriate drug, e.g. Prozac or ther conditions. There is one thing he says, which
makes sense - two things can be true and not
be related.

You sound like you've been through this really
fascinating stage in the (hopefully) evolution of
psychopharmacology, but I am just a layman.

Still reading - back when I'm done with any comments. Hope others find it interesting too.

Squiggles


> I'm perennially confounded in conversations with you, my friend. We are so different in style. I should not have used the word defense without having read the paper. How do you know it's an important paper?
>
> All I saw at pp. 200 and onwards was a very concise and precise definition of the role of anecdote in scientific inquiry. An extremely limited role, which upon revelation seems to raise the hackles of non-scientists. I struggle against it, here, myself. The hackle-raising, I mean. His example re: tonsils and tonsillectomy, is an excellent one.
>
> Lar
>


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