Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: MAOIs

Posted by Jost on May 9, 2006, at 23:27:19

In reply to Re: MAOIs, posted by Caedmon on May 9, 2006, at 19:30:31

> Hi Don,
>
> The figures you quoted, were they from http://www.emedicine.com/EMERG/topic318.htm ? You posted a link to the aapcc's website, but I honestly couldn't make heads or tails of anything on it.
>


The figures Don quoted, unless I'm mistaken (which I might be) were from a "Summary of fatal exposures reported to TESS in 2002" published in the Am J. of Emergency Med.

However, the Summary, as I read it, noted only one death from an maoi, ie parnate; and the cause of death was "ther. err."--ie therapist error, rather than an adverse drug reaction.

Possibly, Don's statistics are from another source. However, the type of AD associated with the highest number of fatalities on this report, by far, was tricyclics, particularly. amitriptyline. Is this the most widely prescribed tricylic?

Most of the deaths were intentional. There are a few other causes, such as "malicious," "adv. react." and "ther. err." The number of adverse reactions is so small that it would seem hard to draw any conclusions from this one report.

Last night I came across a paper--I can't find it now--that suggested that deaths from tricyclics were greater in absolute numbers than those from maois, although a somewhat greater proportion of the maoi fatalities were intentional. The difference didn't seem so great as to make the argument that maois are to be avoided at all costs. Obviously, care must be taken in their use..

I'd be interested in Don's sources, though.

Jost


Share
Tweet  

Thread

 

Post a new follow-up

Your message only Include above post


Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.

 

Start a new thread

 
Google
dr-bob.org www
Search options and examples
[amazon] for
in

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:Jost thread:639045
URL: http://www.dr-bob.org/babble/20060504/msgs/642020.html