Posted by blueberry on May 9, 2006, at 17:56:51
In reply to I need your opinion, if you have the time, posted by UgottaHaveHOPE on May 9, 2006, at 15:18:37
It's tough I know. I'm so sorry things aren't working as effectively as they were before. Seems to happen a lot around here. :-(
If you have any kind of a sex life, I would call your doctor back and ask for lexapro instead of paxil.
I personally would avoid going higher on the seroquel. It's just that it seems fairly easy over time to creep up in dose, but if you ever have to come back down in dose, it will be extremely hard. Antipsychotics are very hard to come off of.
Another thing about seroquel...one of its strong actions is as an a-2 antagonist...it causes a stimulated release of more norepinephrine (like adrenaline). At lower doses it wasn't doing much of that. The higher you go on dose, the more noradrenaline is being stimulated. Higher doses might actually make things worse.
Paxil seems like a decent option to tone down the norepinephrine with a wash of serotonin, and its norepinephrine reuptake (slight) will also squash it down, after a couple weeks of maybe increased anxiety at first.
Other possibilities...lamictal, in case of too much glutamate (excitatory) stimulating all the other neuros. Depakote is usually calming.
See if paxil can help. If not, maybe temporarily raise klono dose for relief and rethink another strategy. There are some types of mania that look like and feel like anxiety. If that's the case, depakote can shut it down in a few days. If you tried it for a week or two and it wasn't helpful, you could drop it knowing it wasn't the one. No long trial needed.
Sorry so long. Just opinion and just trying to help. Some counseling if you can afford it and church could be very very helpful too.
poster:blueberry
thread:641832
URL: http://www.dr-bob.org/babble/20060504/msgs/641894.html