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grapefruit juice-drug interaction

Posted by bassman on May 9, 2006, at 12:26:02

In today's news, we have:
http://news.yahoo.com/s/nm/20060509/hl_nm/grapefruit_dc

the new discovery that furanocoumaridins (sp?) are the guys in grapefruit juice that interfere with the metabolism of some drugs. Ooops, did I say new discovery? Maybe not-here's an article from 2003:

http://ift.confex.com/ift/2003/techprogram/paper_15590.htm

Another thing I like about the new article is that it suggests that the compounds be added to drug formulations so less drug is required. Unfortunately, the furanocoumaridins are poisonous. If you take cyanide with your meds, I'll bet they metabolize more slowly, too. :>} I'm a research scientist, so I'm always astonished when things like this happen...but it is interesting.


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poster:bassman thread:641753
URL: http://www.dr-bob.org/babble/20060504/msgs/641753.html