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Re: Does nicotine inhibit MAO at high doses

Posted by linkadge on May 2, 2006, at 20:38:41

In reply to Re: Does nicotine inhibit MAO at high doses, posted by willyee on May 2, 2006, at 20:26:56

I don't think that beta carbolines are in cola's. Its independant of the caffiene. You can get MAO inhibition from decaff coffee.

I know that some studies show that heavy smokers have about 50% less MAO-A and MAO-B. So it could definately interact with a MAO inhibitor.

The beta carbolines are reversable inhibitors of MAO, meaning that their effects only last about 6-8 hours, and after that normal MAO activity resumes.

So to achieve steady MAO inhibition from beta carbolines, you probably have to smoke or whatever a few times per day.

Linkadge


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