Posted by Michael Bell on May 1, 2006, at 10:54:16
In reply to Re: Dopamine NOT linked with social phobia, posted by anony on May 1, 2006, at 2:14:55
> It looks like the research is rather saying that dopamine IS linked with social phobia...to me.
>
> Am I reading it wrong?They're saying that disfunction of dopamine as far as genes are concerned is not related to SP. They examined the different receptors and noticed no genetic variance between SP subjects and control subjects. However, they point out that there may be a link with dopamine and SP in some other non-genetic manner, and that more research is needed.
On another note, the researches of that well-known study which found the lower binding affinity of dopamine to D2 receptors hypothesized that the poor binding may not be a problem with D2 receptors themselves, but rather that disfunction of another system (i.e. GABA) causes too much dopamine release, and that the D2 receptors have downregulated and become desensitized as a result.
poster:Michael Bell
thread:638640
URL: http://www.dr-bob.org/babble/20060429/msgs/638759.html