Posted by jparsell82 on April 19, 2006, at 10:22:02
http://uk.biz.yahoo.com/060117/81/g1cuh.html
Looks like they've started the launch of Serdolect in Europe now. I've been following this med for awhile. What interests me is that it blocks D2 receptors, but not in the striatum. Maybe a better atypical for social anxiety??? The reason... I read a study on pubmed that found social phobics had low D2 receptor binding potential in the striatum. Perhaps that's why other atypicals have not helped or made my social anxiety worse in the past? Anyways, here's a quote from an information site for sertindole:
"Sertindole promises a restricted receptor and brain site activity. Its activity appears to be specific to D2, 5-HT2 and alpha-1 adrenergic receptors and largely confined to the limbic dopamine system of the brain (without inhibiting activity in the nigrostriatal dopamine system), at least in animal in vivo and in vitro studies.
Sertindole is reported to have an anxiolytic property, to be not sedating and not to impair cognitive functions."
Here's that site: http://www.priory.com/focus5.htm
poster:jparsell82
thread:634760
URL: http://www.dr-bob.org/babble/20060417/msgs/634760.html