Posted by yxibow on April 15, 2006, at 11:05:53
In reply to Klonopin Dosing Schedules...., posted by becksA on April 12, 2006, at 12:05:03
>Is there a recommended best way when it comes to >the half-life of the med?
The approximate in vivo half life is 16 hrs...
>I suppose the actual dosen't matter as everybody >is affected differently
most definately....
>but I've always been insanely tolerant to meds
quite fascinating... I have too as of late anyway
>, and I'm on 14mg daily. I take 5mg at around >8AM, 5 mg at around 1-2 PM, and then 4mg at >around 6-7 PM. Thing is it tends to vary, and as >you can see, I notice that as the day progresses, >I need it quicker and quicker. Does this make >any sense?
As my day progresses my particular disorder gets worse, so that makes sense in an anxiety disorder, one gets more tired and progressively more anxious of the things they deal with during the day.
I thought I was at a high dose at 8 mg of Klonopin when I switched to 160 (then 170 mg) of Valium... wow, 280mg of Valium -- that's a record.
But it is true the technical ceiling of Klonopin is 20mg in adjunctive therapy for petit/grand mal seizures.
So the answer is, generally twice daily. However you have found that it works better for you 3 times daily so it doesn't really matter. Its in your system and the blood level is already there, but you may be benefitting from spikes in plasma level.
Just be careful that 1) you don't have ANY other major CNS depressants in your body at that dose -- including anything more than a really small dose of alcohol nowhere near the time you take a dose and 2) any other sedating medications -- while benzodiazepines are among the safest of psychiatric medicines in terms of -most- side effects, the one you have to be most careful of here is respiratory depression. That is, the drug is calming every muscle, including the ones tha t control your breathing.
So take care and be well. You could be a fast metabolizer, that isnt unknown.
Cheers
-- Jay
poster:yxibow
thread:632169
URL: http://www.dr-bob.org/babble/20060412/msgs/633460.html