Posted by MARTY on April 14, 2006, at 12:11:56
In reply to Re: Attn Linkage..Nardil to Parnate Question. » linkadge, posted by MARTY on April 14, 2006, at 9:02:52
Sorry this post wasn't only for Linkage like my title was saying...
What do you think of this theory:
The monoamines oxidase level is returning to is normal level after 3-5 days. For this theory lets be more conservative/safe and let's say 10 days.
My pdoc think that because Nardil and Parnate works in the same way, stoping a MAOI and starting another should not be a problem since it should not change a lot the MAO level.. letting some MAO in the body which is important since a person with a level of 0 MAO is in big trouble.
But here's my theory: Nardil and Parnate doesn't inhibit the MAO-A and MAO-B in the same proportion. Here's an exemple of the problem that it could cause: If one day after stoping Nardil, which let's say BY EXEMPLE inhibit 75% MAO-A and 25% MAO-B, I start Parnate who would BY EXEMPLE inhibit 25% MAO-A and 75% MAO-B.. I would have in theory, depending on the dose of Nardil and Parnate and etc.. near not much MAO since N-MAO-A 75% + P-MAO-A 25% = MAO-A 100% and N-MAO-B 25% + P-MAO-B 75% = MAO-B 100% ...
Those numbers are fictional and have been picked just to simplify the explanation of my theory.
Anyone thinks it could make sens ?
Thanks for your time and hope you are all well.
Marty
poster:MARTY
thread:632778
URL: http://www.dr-bob.org/babble/20060412/msgs/633061.html