Posted by Sarah T. on April 8, 2006, at 15:33:01
In reply to Increased depression on Adderall, posted by Racer on April 8, 2006, at 11:00:33
Hi Racer,
I had a lot of difficulties with Adderall, and I think those difficulties could be classified as "increased depression." I became withdrawn and very quiet on all types of Adderall (XR and immediate release) and at several different dosages. I am still trying to figure out why this happened. I've tried Adderall a number of times over the past 5 years or so, and I have had the same response every time.
I did very well on Dexedrine, but in spite of doing everything I could to stave off tolerance, I developed a tolerance to it anyway. As you probably know, Adderall is about 69% dextroamphetamine, although the dextroamphetamine in Adderall isn't all dextroamphetamine sulphate. Dexedrine is dextroamphetamine sulphate. Adderall has some dextroamphetamine sulphate in it, but it also has some dextroamphetamine paired with other counter-ions instead of the sulphate that make the molecule less soluble. I have had a problem with solubility with seveal other medications, so it's possible that the salts that make up Adderall just don't dissolve well for me.
Dexedrine is more active in the central nervous system than Adderall, so I think it is more likely to help depression.
By the way, did you try Concerta when you were going through the various formulations for methylphenidate? I ask because although Concerta is methylphenidate, to me, it felt completely different from Ritalin.
I'm interested to hear what you have to say about Buspar. All I know about it is that it's a non-benzodiazapine anxiolytic that was reputed to have some antidepressant properties. Do you think it has an antidepressant effect?
I have to mention that I'm having a lot of computer problems, so if I don't respond right away, that's why.
Sarah
poster:Sarah T.
thread:630542
URL: http://www.dr-bob.org/babble/20060408/msgs/630617.html