Posted by rvanson on March 17, 2006, at 16:33:05
In reply to Re: Abstract-- (MAO-A vs. MAO-B, dopamine), posted by gibber on March 13, 2006, at 21:22:33
> I can't address your question as a whole because I just don't know, but I did want to point out one error in your arguement. Phenylalanine is not converted to phenylethylamine by MAO-B. This must be catalyzed by a different enzyme. MAO-B instead quickly breaks down phenylethylamine, so taking a MAO-B inhibitor will allow PEA to accumulate. Note: I'm taking DLPA and 10mg of selegiline right now and not noticing any strong antidepressive qualities yet.
I have the distinct believe that Emsam will be another flop. I too tried selegiline at higher doses and frankly, it was a waste of time.Check out the drop-out rates in the pre-realese studies of Emsam and I think that one can see that this is a weak drug for major depression.
Having said that, I hope I am mistaken.
poster:rvanson
thread:619679
URL: http://www.dr-bob.org/babble/20060315/msgs/621365.html