Posted by linkadge on March 14, 2006, at 21:14:42
In reply to Sleep Deprivation AntiDepressants, posted by tessellated on March 14, 2006, at 17:46:34
Sleep deprivation affects the monoamines. Sleep deprivation increases hippocampal serotonin, sometimes that inrease lasts a few days after the SD night.
SD actually affects all three of the monoamines to varying extends and in different ways.
Sleep deprivation increases the sensitivity of the d2 receptors. It is funny, because sucessfull treatment with many antidepressants increases the sensitivity of the d2 receptors.
I honestly don't understand it.
The sucess of SD tells me that the brain has full capability of putting itself into remission.
But its complex, because when you induce depression in animals (by stressing them unavoidably) they develop sleep abnormalities, in particular REM sleep abnormalities.
So, I don't get it, but it angers me that a cure is "right there" but just inacessable.
SSRI's only worked for me when they reduced the amount of sleep I got.
Linkadge
poster:linkadge
thread:619892
URL: http://www.dr-bob.org/babble/20060310/msgs/620379.html