Posted by TylerJ on March 11, 2006, at 17:51:37
In reply to Re: Questions for Chairman _MAO, posted by Chairman_MAO on March 11, 2006, at 17:33:58
> The major problem I had was that the insomnia came back. The insomnia from Parnate is the most severe insomnia I've ever experienced, next to perhaps high doses of LSD or amphetamine. Given that I have PRIMARY insomnia, this was a big problem. If I had a less dogmatic doctor at the time I may have stayed on Parnate, as perhaps then I could've gotten strong enough downers to sleep well.
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> It never pooped out. I agree with Ivan Goldberg's assertion 100% that the biggest reason for treatment failure with Parnate is inadequate dosing. IMHO, the true therapeutic dose is ~1.5mg/kg. A 60mg/day maximum is not based in any reason except fear of litigation, perhaps, and that the drug only comes in 10mg tablets is absurd. It's basically a psychostimulant with 1/10th the potency of d-amphetamine.
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> As for augmentation, please tell me what you are seeking to treat. Buprenorphine is a fantastic antidepressant.I was on Parnate in 1997 for 2 1/2 mos. it worked great and then for lack of a better word it pooped out...or like you say maybe the dose i was on was inadaquate. I was on 140 mgs.
Me and my pdoc are prepared to go higher this time if needed-I have no doubt he'll take me to 200 if needed. I'm currently on 90mgs and doing very well. What I'm looking for is probably based on fear that I will lose my response and won't be able to get it back. Augmentation meds such as mood stabilizes, other ad's, anti-convusants, beta-blockers, and anything you can think of to keep parnate working loner and better, of course when and if needed only. Again, my doc won't do stimulants. Please be honest with me, if you think only getting the dose right is what matters, and augmentation is not neccessary..I will definitely respect your opinion. Thanks.Tyler
poster:TylerJ
thread:618914
URL: http://www.dr-bob.org/babble/20060310/msgs/618999.html