Posted by Chairman_MAO on March 10, 2006, at 12:22:09
In reply to Any stimulant less likely to raise blood pressure?, posted by Racer on March 9, 2006, at 20:04:26
Pemoline has the least cardiovascular toxicity of any (marketed psychostimulant). However, I believe it has been or will be withdrawn due to concerns over hepatotoxicity.
In second place is d-methamphetamine (Desoxyn), which has a much higher therapeutic index, i.e. the dose required for a CNS effect vis a vis the dose causing untoward effects or toxicity, than d-amphetamine or methylphenidate. This is due largely due to markedly higher lipid solubility.
poster:Chairman_MAO
thread:618093
URL: http://www.dr-bob.org/babble/20060310/msgs/618360.html