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Re: oh » linkadge

Posted by Chairman_MAO on March 9, 2006, at 23:29:33

In reply to Re: oh » Chairman_MAO, posted by linkadge on March 9, 2006, at 9:13:01

What dose of parnate were you taking?

What you are describing sounds like an initial response to the psychostimulant effect that waned.
Yes, many people on all sorts of medications experience waning effectiveness; is it the medicine or different life conditions? Probably both...

That said, MAOIs+d-amphetamine probably is a little more robust than effexor in terms of poop-out. ;)

If you were at 1.5mg/kg Parnate and told me it pooped out, I'd be surprised. Then I Would urge to try an augmentation strategy or perhaps switch to Nardil + psychostimulant/etc. You will not have that same "psychotic" feeling that you had.

BTW, that "psychotic" feeling could have been taking too LOW a dose such that the dopaminergic effects of TCP and metabolites wasn't counterbalanced enough by increased concentrations of intrasynaptic SE. When I took 30mg (over a day) once after being on 60mg for about a week before, I found myself feeling paranoid. Back up to 60 (0.7mg/kg, right on target) and it went away.


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