Posted by yxibow on February 17, 2006, at 2:40:35
In reply to Re: Whats best for GI problems, posted by Christian10 on February 16, 2006, at 18:57:38
> I developed a GI problem after taking paroxetine for almost three years. Now every time i want to start treatment with it again (because it was one of the best things i tried for my social anxiety along with Klonopin) my guts get so damn swell that i have to stop it inmediately.
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> Do you think that taking paroxetine along with a 5ht3 blocker would be of any benefit for my situation?? Thanks
If the same drug attacks 5HT3, which is known with SSRIs because they're not completely perfect and clean and will hit 5HT3 as well as the other 5HT receptors (most all your serotonin receptors are in your guit), in you, several times, one might consider a change to another drug. Effexor has been approved for Social Anxiety Disorder and it might be worth a try.If you really want to try Paxil again, you're going to have to go for the long haul... the problems with 5HT3 will dissappear, they may come back again. But it sound suspicious after 3 years that it is developing -- are you absolutely sure you don't have an ulcer related disorder instead ?
I would experiment with a copious amount -- i.e. an entire root (they're not particularly harmful) (your taste buds may be different from mine) of raw ginger, easily gotten from your local Trader Joes or supermarket. It has a mild 5HT3 blockade. If that does nothing at all, I would look with your GP to something else other than the Paxil as the cause.
Have you tried Prilosec OTC for 14 days ? That may be another test that it is not 5HT3.
Also a trial of Zantac or similar OTC would be another test.
Usually the GI troubles with SSRIs and SSNRIs start in the first few weeks and go away after a while or with dosage adjustments.
I hope your tummy feels better-- Jay
poster:yxibow
thread:608066
URL: http://www.dr-bob.org/babble/20060212/msgs/610526.html